کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6114524 1591146 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Idiopathic aplastic anemia: Diagnosis and classification
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Idiopathic aplastic anemia: Diagnosis and classification
چکیده انگلیسی
Aplastic anemia (AA) is a disease characterized by pancytopenia and hypoplastic bone marrow caused by the decrease of hematopoietic stem cells. The pathogenesis of AA is complex and involves an abnormal hematopoietic microenvironment, hematopoietic stem cell/progenitor cell deficiencies and immunity disorders. Survival in severe aplastic anemia (SAA) has markedly improved in the past 4 decades because of advances in hematopoietic stem cell transplantation, immunosuppressive and biologic drugs, and supportive care. Herein, we will update the main issues concern AA according to our literature review.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 13, Issues 4–5, April–May 2014, Pages 569-573
نویسندگان
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