کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6118515 | 1591853 | 2009 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Epidemiology of invasive pneumococcal disease in the Arabian Peninsula and Egypt
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
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چکیده انگلیسی
Invasive pneumococcal disease (IPD) causes considerable morbidity and mortality among children worldwide. This review describes the burden of disease and pneumococcal serotypes/serogroups causing disease in children in the Arabian Peninsula and Egypt identified from a literature search from 1990 to 2007. The incidence of IPD in children aged â¤5 years ranged from 3.4 to 53.5 per 100 000. Bacteraemia cases were responsible for 61-100% (children <2 years) of total IPD. Pneumococcal meningitis cases ranged from 3% to 25% (<2 years) and from 7% to 30% (â¤5 years). The most common IPD serotypes/serogroups were 14, 23F, 6B, 19F and 6A (â¤5 years). Circulating serotypes/serogroups causing IPD potentially covered by the 7-valent pneumococcal conjugate vaccine (PCV-7) ranged from 49% to 83% (<2 years) and from 61% to 69% (â¤5 years). Penicillin resistance among invasive isolates ranged from 0% to 78%. Case fatality and morbidity rates for pneumococcal meningitis were 0-22% and 10-62%, respectively. Incidence and morbidity data for meningitis and bacteraemia demonstrate a substantial vaccine-preventable burden of IPD in young children. Standardisation of definitions and development of improved regional surveillance/reporting would enable the region to measure better the impact of prevention strategies for IPD, such as infant-based immunisation programmes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Antimicrobial Agents - Volume 33, Issue 5, May 2009, Pages 410.e1-410.e9
Journal: International Journal of Antimicrobial Agents - Volume 33, Issue 5, May 2009, Pages 410.e1-410.e9
نویسندگان
Atef Shibl, Ziad Memish, Stephen Pelton,