Severe encephalitis in a previously healthy teenager: Who is the real culprit?

- We described a case of severe encephalitis in an immunocompetent teenager.
- Initial virological results pointed unconvincingly to an EBV primary infection.
- Parvovirus B19 infection was discovered by chance, as etiology of the encephalitis.
- Parvovirus B19 testing should be included in the workup of encephalitis.