کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6121392 1219011 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy
چکیده انگلیسی
The mechanism of elite control of HIV-1 replication is not fully understood. While immunosuppression due to rituximab based chemotherapy has been associated with increased replication of HBV, CMV, and HIV-1, control of replication-competent HIV-1 was maintained in an elite controller/suppressor treated with a regimen that included vincristine, cyclophosphamide, prednisone, four rounds of plasmapheresis and ten cycles of rituximab. The data suggests that de-novo antibody responses do not play a significant role in the control of viral replication in these patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Virology - Volume 51, Issue 3, July 2011, Pages 195-198
نویسندگان
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