Elevated tibiofemoral articular contact stress predicts risk for bone marrow lesions and cartilage damage at 30Â months

Detection of higher contact stress 30 months prior to structural worsening suggests an etiological role for mechanical loading. Estimation of articular contact stress with DEA is an efficient and accurate means of predicting subregion-specific knee joint worsening and may be useful in guiding prognosis and treatment.