کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6181910 | 1253520 | 2014 | 9 صفحه PDF | دانلود رایگان |
ObjectiveTo determine whether there is a difference in ongoing pregnancy rates (PRs) between patients undergoing IUI with strict sperm morphology â¤4% compared with >4% on initial semen analysis.DesignRetrospective chart review with multivariate analysis.SettingAcademic outpatient reproductive center.Patient(s)A total of 408 couples with male and/or female factor infertility and known strict sperm morphology (SSM).Intervention(s)A total of 856 IUIs with partner's sperm (IUI-P).Main Outcome Measure(s)Ongoing PRs based on ultrasound documentation of intrauterine pregnancy with fetal heart tones.Result(s)There is no statistically significant difference in per cycle PRs when comparing patients with a strict sperm morphology of â¤4% versus >4% who undergo IUI-P (17.3% vs. 16.7%; odds ratio 0.954, 95% confidence interval 0.66-1.37). Multiple potential confounding factors were assessed using multivariate analysis.Conclusion(s)Strict sperm morphology â¤4% is not associated with lower PRs in couples undergoing IUI-P, and thus should not be the sole reason for advancing to IVF.
Journal: Fertility and Sterility - Volume 102, Issue 6, December 2014, Pages 1584-1590.e2