IOP telemetry in the nonhuman primate

- Nontechnical review focused on continuous IOP measurement in NHPs.
- Focus on glaucoma, and why continuous IOP measurement might be important in disease.
- Review of how ocular biomechanics influence IOP fluctuations and dynamics.
- Review the current systems and data on IOP telemetry in NHPs.
- Review the technical challenges and emerging approaches to IOP telemetry.

This review is focused on continuous IOP monitoring using telemetry systems in the nonhuman primate (NHP), presented in the context that IOP fluctuations at various timescales may be involved in glaucoma pathogenesis and progression. We use glaucoma as the primary framework to discuss how the dynamic nature of IOP might change with age, racial heritage, and disease in the context of glaucoma susceptibility and progression. We focus on the limited work that has been published in IOP telemetry in NHPs, as well as the emerging data and approaches. We review the ongoing efforts to measure continuous IOP, and the strengths, weaknesses and general pitfalls of the various approaches.