کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
622221 | 882614 | 2010 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Removal of albumin-bound toxins from albumin-containing solutions: Tryptophan fixed-bed adsorption on activated carbon Removal of albumin-bound toxins from albumin-containing solutions: Tryptophan fixed-bed adsorption on activated carbon](/preview/png/622221.png)
Fixed-bed adsorption on activated carbon is a common blood detoxification technique implemented in liver support devices to remove different types of toxins, among which is tryptophan.In this paper, fixed-bed adsorption kinetics of tryptophan on activated carbon were investigated. Experimental tryptophan breakthrough curves were obtained at different feed flow rates, both in albumin-free and albumin-containing solutions. A mathematical model based on linear driving force mass transfer kinetics was used to correlate data obtained with albumin-free solutions; subsequently, the results were successfully used to predict tryptophan breakthrough curves obtained with albumin-containing solutions, accounting only for the effect of albumin over tryptophan adsorption equilibrium.
Journal: Chemical Engineering Research and Design - Volume 88, Issue 8, August 2010, Pages 1018–1023