Major depression treatment in Germany-descriptive analysis of health insurance fund routine data and assessment of guideline-adherence

- Description of routine treatment reality and analysis of guideline fidelity in first episode Major Depressive Disorder in Germany.
- Method: descriptive analysis of health insurance fund routine data.
- Population size >7,500,000 individuals.
- Overall, routine practice was oriented upon the German guidelines recommendations.
- However some aspects could be identified that bear potential for improvements; especially, pharmacotherapy and psychotherapy in patients treated by general practitioners.

BackgroundGuideline oriented treatment strategies of Major depressive disorder (MDD) improve treatment outcomes and reduce risks of chronicity and recurrence.AimsDescription of routine treatment reality and analysis of guideline fidelity in first episode MDD in Germany. Indicators: patients with severe or psychotic depression or severe psychiatric comorbidities' treatment by specialists, adequate antidepressant pharmacotherapy, permanent treatment with more than one antidepressant, long-term benzodiazepine treatment and provision of psychotherapy.MethodDescriptive analysis of routine data of the German statutory health insurance fund Barmer GEK in the index year 2011 that covers a population of 7,501,110.Results236,843 patients were diagnosed a depressive episode. 53.0% of the patients with severe depression, 34.4% with psychotic depression and 50.9% with severe psychiatric comorbidities were treated by specialists; of the patients treated by a general practitioner 48.1% with severe and 47.3% with psychotic depression received an antidepressant; 9.7% of all patients with MDD got two antidepressants simultaneously; 8.3% received longterm benzodiazepine prescriptions; 26.1% got psychotherapy.Limitationsthe analyses depends on the indicators definitions that cannot cope with the variety of individual treatment path; comparison with guidelines was complicated by a large fraction of patients with recurrent MDD that was wrongly diagnosed with first episode depression; due to the data structure, not all guideline recommendations could be examinedConclusionsRoutine practice was oriented upon the guidelines recommendations. However some aspects could be identified that bear potential for improvements.