کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6233102 1608171 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Omega-6 fatty acids and greater likelihood of suicide risk and major depression in early pregnancy
ترجمه فارسی عنوان
اسیدهای چرب امگا 6 و بیشتر احتمال ابتلا به خودکشی و افسردگی عمده در اوایل بارداری
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی

ObjectiveTo estimate the prevalence of suicide risk (SR) and major depressive episodes (MDEs) in early pregnancy, as well as the relationship of serum fatty acid status to these outcomes.MethodsCross-sectional analyses were performed on data from 234 pregnant women enrolled in a prospective cohort study in Rio de Janeiro, Brazil. SR and MDE were defined according to the Mini International Neuropsychiatric Interview. Fatty acid compositions were determined for serum samples obtained between the 6th and 13th gestational week. Fatty acid data were expressed as the percent of total fatty acids, converted to Z scores and then entered as continuous variables in logistic regression models.ResultsThe prevalence of SR was 19.6% and that of MDE was 17.0%. In the adjusted logistic regressions, a higher likelihood of SR was observed among women with higher arachidonic acid levels [AA (20:4, n-6): OR=1.45, 95%CI 1.02-2.07] and adrenic acid levels [AdA (22:4, n-6): OR=1.43, 95%CI 1.01-2.04]. A higher likelihood of MDE was also observed among women with higher AA levels [OR=1.47, 95%CI 1.03-2.10] and AdA levels [OR=1.59, 95%CI 1.09-2.32].ConclusionHigher serum levels of AA and AdA were associated with a greater likelihood of SR and MDE among pregnant Brazilian women.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volumes 152–154, January 2014, Pages 76-82
نویسندگان
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