کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6240326 1280420 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acute effects of viral respiratory tract infections on sputum bacterial density during CF pulmonary exacerbations
ترجمه فارسی عنوان
اثرات حاد عفونت های دستگاه تنفسی ویروسی بر تراکم باکتری های خلط در طی افزایش تشدید درد ریوی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
چکیده انگلیسی

BackgroundAirway proliferation of Pseudomonas aeruginosa bacteria is thought to trigger CF exacerbations and may be affected by the presence of viral infections.MethodsA 2-year prospective study was conducted on 35 adults with CF. P. aeruginosa sputum density was analyzed during stable, exacerbation and post exacerbation assessments. Upon exacerbation, samples were sent for PCR detection of respiratory viruses and the sputum density of P. aeruginosa in patients with a viral infection versus those without was compared.ResultsTwenty-two patients experienced 30 exacerbations during the study period; 50% were associated with a viral infection. There was no change in sputum density of P. aeruginosa from the stable to exacerbation state when measured by quantitative culture or by PCR. Virus-associated exacerbations did not result in significant increases in P. aeruginosa sputum density compared to non-viral exacerbations.ConclusionSputum density of P. aeruginosa was not increased at the time of CF exacerbation and was not influenced by the presence of viral infection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cystic Fibrosis - Volume 14, Issue 4, July 2015, Pages 482-489
نویسندگان
, , , , , , , , , , ,