کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6254522 | 1288445 | 2012 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Oncology/EndocrineHepatic resection for huge (>15 cm) multinodular HCC with macrovascular invasion Oncology/EndocrineHepatic resection for huge (>15 cm) multinodular HCC with macrovascular invasion](/preview/png/6254522.png)
BackgroundSurgical resection has routinely not been recommended for patients with huge (>15 cm) multinodular lesions and macrovascular invasion (advanced-stage hepatocellular carcinoma [HCC] patients) because of high operative mortality, recurrence rate, and lack of survival benefit.MethodsA retrospective study of 1425 patients was carried out, of which 1245 patients met EASL/AASLD criteria for hepatic resection (HR-EA group), 116 were surgically treated advanced-stage HCC patients (HR-AS group), and 64 were advanced-stage HCC patients receiving nonsurgical treatments (N-AS group).ConclusionHR may still be suitable for the HCC patients with huge (>15 cm) multinodular lesions and macrovascular invasion in selected cases. Advanced-stage HCC patients without liver cirrhosis and with a tumor-free resection margin could enjoy longer survival and lower recurrence. Preoperative and/or postoperative TACE provides no survival benefits for advanced-stage HCC patients.
Journal: Journal of Surgical Research - Volume 178, Issue 2, December 2012, Pages 743-750