کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6258856 1612976 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research reportThe diurnal variation of performance of the novel location recognition task in male rats
ترجمه فارسی عنوان
گزارش تحقیق تنوع روزانه عملکرد کار جدید شناسایی مکان در موش صحرایی نر
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- We examined the circadian rhythm of performance in the novel location recognition (NLR) task using rats.
- The performance was better during the dark period than during the light period.
- Artificial change of melatonin level modulated the diurnal variation of performance.

Circadian changes of performance have been reported in various kinds of learning task. However, the diurnal variation of performance in hippocampus-dependent learning tasks remains unclear. In the present study, rats were subjected to the novel location recognition (NLR) task as well as the novel object recognition (NOR) task to examine whether the circadian pattern of hippocampus-dependent task performance was similar to that in tasks in which brain regions other than the hippocampus contribute. The performance in the NOR task was relatively constant irrespective of the time of day, while the performance in the NLR task was higher at night than during the daytime. When the pineal hormone melatonin was injected into rats before the training phase in order to examine its effects on the pattern of circadian changes of NLR performance, rats showed improvement of performance in the daytime, but impairment at night. These results suggest that the pattern of circadian variation of memory performance depends on the type of task, and that the effects of exogenous melatonin on learning performance vary with the time of day.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 256, 1 November 2013, Pages 488-493
نویسندگان
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