Gamma oscillations in schizophrenia: Mechanisms and clinical significance

► Irregular γ oscillations in schizophrenia could account for cognitive deficits. ► Irregular γ oscillations may serve as endophenotypes for schizophrenia. ► Neurobiological basis of γ oscillations in relation to schizophrenia are explained. ► Paradigms for investigating irregular γ oscillations are reviewed. ► Limitations of current findings and future research directions are discussed.