Galectin-3 expression in delayed neuronal death of hippocampal CA1 following transient forebrain ischemia, and its inhibition by hypothermia

► This is the first study to show that galectin-3 is up-regulated in delayed neuronal death. ► Galectin-3 expression is localized within the hippocampal CA1 region and observed only in cells that express Iba-1. ► Hypothermia prevents the expression of galectin-3 up-regulation.