کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6282392 | 1615140 | 2014 | 5 صفحه PDF | دانلود رایگان |
- Aged rodents exhibit alterations in cognitive functions.
- The goal was to evaluate the effect of age in the incentive' assessment.
- We use an emotional-cognitive protocol and only a cognitive one.
- Aged rats had a mild cognitive impairment in both procedures.
Response to a reinforcer is affected by prior experience with different reward values of that reward, a phenomenon known as incentive relativity. Two different procedures to study this phenomenon are the incentive downshift (ID) and the consummatory anticipatory negative contrast (cANC), the former is an emotional-cognitive protocol and the latter cognitive one. Aged rodents, as also well described in aged humans, exhibit alterations in cognitive functions. The main goal of this work was to evaluate the effect of age in the incentive' assessment using these two procedures. The results indicated that aged rats had an adequate assessment of the rewards but their performance is not completely comparable to that of young subjects. They recover faster from the ID and they had a cognitive impairment in the cANC. The results are discussed in relation to age-related changes in memory and emotion.
Journal: Neuroscience Letters - Volume 559, 24 January 2014, Pages 122-126