کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6282398 | 1615140 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Efferent-mediated reduction in cochlear gain does not alter tuning estimates from stimulus-frequency otoacoustic emission group delays
ترجمه فارسی عنوان
کاهش اثر متقابل اگزرنت در افزایش جذب کچلی تغییرات تنظیم شده از تاخیر گروه های انتشار اتوآکوستیک فرکانس محرک را تغییر نمی دهد
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
CASSFOAEPTCMOCOHCOAE - CESmedial olivocochlear - mediv olivocochlearOtoacoustic emission - انتشار OtoacousticOtoacoustic emissions - انتشارات OtoacousticHumans - انسانContralateral acoustic stimulation - تحریک آکوستیک متعاقب جانبیCochlea - حلزون گوشContralateral suppression - سرکوب انتفاعیouter hair cell - سلول بیرونی موAuditory nerve - عصب شنواییbasilar membrane - غشاء basilarCharacteristic Frequency - فرکانس مشخصهpsychophysical tuning curve - منحنی تنظیم روانشناختی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
The existence of efferent feedback from cortical and subcortical brain centers to the hair cells of the cochlea has been recognized for many years, but the role that efferent neurons play in hearing is not completely known. Stimulation of medial olivocochlear (MOC) efferent neurons suppresses sound-evoked basilar membrane responses and changes the tuning of single auditory nerve fibers in animal models. Both of these effects are linked to a MOC-induced reduction in the gain of the cochlear amplification provided by outer hair cells. To non-invasively examine the link between cochlear suppression and tuning in humans, stimulus-frequency otoacoustic emissions (SFOAEs) were recorded in conditions with and without contralateral acoustic stimulation (CAS) from 28 normal-hearing participants. SFOAEs were measured using clusters of closely-spaced probe-tone frequencies centered near 1.4 and 2.0 kHz. An index of cochlear tuning, QERB, was calculated based on measures of SFOAE group delay at both 1.4 and 2.0 kHz. A statistically significant (p < 0.01) decrease in SFOAE levels acquired during CAS was detected only for the SFOAE cluster centered at 2 kHz. No statistically significant differences in QERB were found between conditions with and without CAS at 1.4 and 2.0 kHz. These findings suggest that in humans, tuning based on SFOAE group delay estimates is not appreciably altered at cochlear locations with MOC efferent-induced reductions in cochlear gain.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 559, 24 January 2014, Pages 132-135
Journal: Neuroscience Letters - Volume 559, 24 January 2014, Pages 132-135
نویسندگان
Shaum P. Bhagat, Chelsea Kilgore,