Adult rat hippocampus soluble factors: A novel transplantation model mimicking intracranial microenvironment for tracing the induction and differentiation of adipose-derived stromal cells in vitro

► We constructed a novel model to trace ADSCs development in vitro. ► The formation of NSCs from ADSCs was found in hippocampus soluble factors firstly. ► We explored the effect between ADSCs and microenvironment alone. ► Chromosomes were analyzed of ADSCs undergoing passage.