Neuroprotective effects of uridine in a rat model of neonatal hypoxic-ischemic encephalopathy

► Uridine is the principal pyrimidine in humans and a membrane phospholipid precursor. ► Uridine treatment reduces brain infarction and apoptosis in rat neonatal HIE model. ► This is the first study to report cerebroprotection by uridine in rat neonatal HIE.