Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT1A and 5-HT1B receptors disruption in mice

► Deletion of both 5-HT1A and 5-HT1B receptors induce higher emotionality in mice. ► Behavior was associated with 723 differentially expressed genes in the hippocampus ► Ingenuity analyses revealed gene changes associated with neurogenesis function ► Cell survival but not proliferation was decreased in the hippocampus of mutant-mice.