The effect of galectin-3 genetic variants on the susceptibility and prognosis of gliomas in a Chinese population

► The genotype distribution at galectin-3 +292 was significantly different between gliomas patient and control groups. ► The A/A genotype of galectin-3 +292 represented a higher risk factor and shorter overall survival period than AC+CC genotype. ► The A/A genotype of galectin-3 +292 represented a shorter mean overall survival period than AC+CC genotype.