کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6284102 1296666 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells
چکیده انگلیسی
► Induced pluripotent stem cells (iPSCs) were generated from autistic patients. ► The iPSCs lines had traits similar to naturally occurring stem cells populations. ► Embryoid bodies with germ layer characteristics were derived from ASD-specific iPSC. ► Mature GABAergic neurons could be differentiated from the ASD-specific iPSC. ► iPSC provide valuable reagents for the characterization of the pathology of autism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 516, Issue 1, 10 May 2012, Pages 9-14
نویسندگان
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