Enriched odor exposure decrease tau phosphorylation in the rat hippocampus and cortex

► Short-term odor enrichment did not affect the phosphorylation of tau. ► Long-term odor exposure attenuated tau phosphorylation. ► Reduction of tau phosphorylation localized in the dendrites of CA1/CA3 neurons. ► The reduction of tau phosphorylation also located in some of cortex neurons.