Improving sensitivity of EEG-fMRI studies in epilepsy: The role of sleep-specific activity

► The influence of sleep specific potentials on the analysis of fMRI data was measured. ► 11 sleeping children suffering from focal epilepsies were scanned using EEG-fMRI. ► Additional to conventional statistical model, sleep specific potentials were included. ► Spatial correspondence between epileptic focus and activation pattern increased.