Investigating the effects of adult neural stem cell transplantation by lumbar puncture in transient cerebral ischemia

► The lumbar puncture is a safe method to inject neural stem cells (NSCs). ► The NSCs can migrate from lumbar region to the subependymal zone. ► The NSCs are able to differentiate to different neuronal and glial cells. ► Transplanted NSCs improve the coordination in movement in ischemic animals.