Clustered K+ channel complexes in axons

▶ There exists a diverse repertoire of clustered voltage-gated K+ channels in axons. ▶ Axonal K+ channels play critical roles in axonal physiology. ▶ Axon initial segment K+ channels are clustered through interactions with scaffolds. ▶ Nodal and juxtaparanodal K+ channels are clustered through neuron-glia interactions.