Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain

▶ FK506 increases basal dendritic spine density on layer II-III pyramidal neurons. ▶ FK506 increases branching of basal dendritic tree of layer II-III pyramidal neurons. ▶ Calcineurin inhibition changes branching and spine density in healthy adult brain.