کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6287537 1615598 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research paperAuditory evoked magnetic fields in individuals with tinnitus
ترجمه فارسی عنوان
گوش شنوایی باعث ایجاد میدان مغناطیسی در افراد مبتلا به وزوز گوش می شود
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
چکیده انگلیسی


- We use MEG to compare evoked responses in participants with tinnitus and controls.
- We compare N1m responses to control, edge, tinnitus and hearing loss tone.
- N1m amplitudes to the tinnitus and hearing loss tones are reduced.
- Differences in N1m amplitudes are related to hearing loss rather than tinnitus.
- There are no tinnitus-specific changes in the pattern of N1m responses.

Some forms of tinnitus are likely to be perceptual consequences of altered neural activity in the central auditory system triggered by damage to the auditory periphery. Animal studies report changes in the evoked responses after noise exposure or ototoxic drugs in inferior colliculus and auditory cortex. However, human electrophysiological evidence is rather equivocal: increased, reduced or no difference in N1/N1m evoked amplitudes and latencies in tinnitus participants have been reported.The present study used magnetoencephalography to seek evidence for altered evoked responses in people with tinnitus compared to controls (hearing loss matched and normal hearing) in four different stimulus categories (a control tone, a tone corresponding to the audiometric edge, to the dominant tinnitus pitch and a tone within the area of hearing loss). Results revealed that amplitudes of the evoked responses differed depending on the tone category. N1m amplitude to the dominant tinnitus pitch and the frequency within the area of hearing loss were reduced compared to the other two categories. Given that tinnitus pitch is typically within the area of hearing loss, the differences in the evoked responses pattern in tinnitus participants seem to be related more to the hearing loss than to the presence of tinnitus.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hearing Research - Volume 302, August 2013, Pages 50-59
نویسندگان
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