کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6288101 1300434 2015 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genomes, neurotoxins and biology of Clostridium botulinum Group I and Group II
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Genomes, neurotoxins and biology of Clostridium botulinum Group I and Group II
چکیده انگلیسی
Recent developments in whole genome sequencing have made a substantial contribution to understanding the genomes, neurotoxins and biology of Clostridium botulinum Group I (proteolytic C. botulinum) and C. botulinum Group II (non-proteolytic C. botulinum). Two different approaches are used to study genomics in these bacteria; comparative whole genome microarrays and direct comparison of complete genome DNA sequences. The properties of the different types of neurotoxin formed, and different neurotoxin gene clusters found in C. botulinum Groups I and II are explored. Specific examples of botulinum neurotoxin genes are chosen for an in-depth discussion of neurotoxin gene evolution. The most recent cases of foodborne botulism are summarised.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Microbiology - Volume 166, Issue 4, May 2015, Pages 303-317
نویسندگان
, ,