Application of the Central Limit Theorem in microbial risk assessment: High number of servings reduces the Coefficient of Variation of food-borne burden-of-illness

► The Central Limit Theorem was applied in understanding microbial risk in foods. ► High numbers of servings decrease the Coefficient of Variation of food-borne diseases. ► The CLT hypothesis was proven by in silico and in vivo data. ► Classical statistics were successfully compared with probabilistic risk assessment.