Oral vaccination of mice with Trichinella spiralis nudix hydrolase DNA vaccine delivered by attenuated Salmonella elicited protective immunity

- Recombinant Salmonella invasion process was similar to natural Trichinella infection.
- Oral immunization of mice with TsNd elicited a mucosal and systemic immune response.
- Vaccination with TsNd produced a partial protection against T. spiralis infection.
- TsNd could be considered as a potential vaccine antigen against trichinellosis.