Altering the motility of Trypanosoma cruzi with rabbit polyclonal anti-peptide antibodies reduces infection to susceptible mammalian cells

- The immunogenicity of a peptide derived from Trypanosoma cruzi was increased.
- Polyclonal anti-peptide antibodies recognize live T. cruzi forms.
- Anti-TcTLE peptide antibodies reduce T. cruzi infection to human astrocytes.
- An imaging system tracks the parasite's flagellum and estimates their reduction speed due to antibodies
- Reducing trypomastigote motility with anti-T. cruzi polyclonal antibodies.