A putative role for inosine 5′ monophosphate dehydrogenase (IMPDH) in Leishmania amazonensis programmed cell death

- Small percentage of Leishmania amazonensis undergoes programmed cell death (PCD) under heat shock.
- We correlated inosine 5′ monophosphate dehydrogenase and PCD in L. amazonensis.
- We suggest the involvement of purine metabolism in PCD during Leishmania infection.