Purification and kinetic analysis of cytosolic and mitochondrial thioredoxin glutathione reductase extracted from Taenia solium cysticerci

- Thioredoxin glutathione reductases (TGRs) from Taenia solium tissues were purified.
- T. solium TGRs are multifunctional enzymes as classic TGRs described.
- Hysteretic kinetic properties showed both cytoplasm and mitochondrial T. solium TGRs.
- T. solium TGRs as selenoproteins were inhibited by nanomolar amounts of auranofin.
- Thioredoxin and glutathione systems are now demonstrated simultaneously in T. solium.