Leishmanicidal activity of amphotericin B encapsulated in PLGA-DMSA nanoparticles to treat cutaneous leishmaniasis in C57BL/6 mice

- D-AMB and Nano-D-AMB had the same efficacy to reduce paw diameter of infected mice.
- Nano-D-AMB promoted a greater reduction in parasite number and cell viability.
- Nano-D-AMB favored a longer interval between drug administrations.