Liposomal-lupane system as alternative chemotherapy against cutaneous leishmaniasis: Macrophage as target cell

- Liposomal-lupane is able to decrease the growth/survival of Leishmania amastigotes.
- The formulation could inhibit the size of paw lesions in BALB/c-infected mice.
- Liposomes induce IL-12 and decrease IL-10 levels for the resolution of infection.