In vitro activity of N-benzenesulfonylbenzotriazole on Trypanosoma cruzi epimastigote and trypomastigote forms

► N-Benzenesulfonylbenzotriazole (BSBZT) showed activity against Trypanosoma cruzi. ► Benznidazole (BZL), BSBZT and benzotriazole (BZT) were tested in parallel. ► BSBZT reduced the number of epimastigotes and trypomastigotes. ► Size reduction of epimastigotes was detected by flow cytometry. ► BSBZT presented low cytotoxic and hemolytic activities.