Effect of garlic and allium-derived products on the growth and metabolism of Spironucleus vortens

► No satisfactory chemotherapies available for the treatment of spironucleosis. ► Allium-derived compounds had an inhibitory effect on Spironucleus vortens. ► Dithiins were most potent, followed by ajoene, raw garlic and allicin. ► Inhibitory concentrations much higher than for other microorganisms investigated.