کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6313070 | 1619037 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations
ترجمه فارسی عنوان
پیاده سازی تکنیک های بررسی سیستماتیک در ارزیابی ریسک های شیمیایی: چالش ها، فرصت ها و توصیه ها
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کلمات کلیدی
ارزیابی ریسک، سنتز تحقیق، محیط، مواد شیمیایی، بررسی سیستماتیک، سم شناسی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
Systematic review (SR) is a rigorous, protocol-driven approach designed to minimise error and bias when summarising the body of research evidence relevant to a specific scientific question. Taking as a comparator the use of SR in synthesising research in healthcare, we argue that SR methods could also pave the way for a “step change” in the transparency, objectivity and communication of chemical risk assessments (CRA) in Europe and elsewhere. We suggest that current controversies around the safety of certain chemicals are partly due to limitations in current CRA procedures which have contributed to ambiguity about the health risks posed by these substances. We present an overview of how SR methods can be applied to the assessment of risks from chemicals, and indicate how challenges in adapting SR methods from healthcare research to the CRA context might be overcome. Regarding the latter, we report the outcomes from a workshop exploring how to increase uptake of SR methods, attended by experts representing a wide range of fields related to chemical toxicology, risk analysis and SR. Priorities which were identified include: the conduct of CRA-focused prototype SRs; the development of a recognised standard of reporting and conduct for SRs in toxicology and CRA; and establishing a network to facilitate research, communication and training in SR methods. We see this paper as a milestone in the creation of a research climate that fosters communication between experts in CRA and SR and facilitates wider uptake of SR methods into CRA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environment International - Volumes 92â93, JulyâAugust 2016, Pages 556-564
Journal: Environment International - Volumes 92â93, JulyâAugust 2016, Pages 556-564
نویسندگان
Paul Whaley, Crispin Halsall, Marlene Ã
gerstrand, Elisa Aiassa, Diane Benford, Gary Bilotta, David Coggon, Chris Collins, Ciara Dempsey, Raquel Duarte-Davidson, Rex FitzGerald, Malyka Galay-Burgos, David Gee, Sebastian Hoffmann, Juleen Lam,