A methodology for evaluating the influence of diets and intergenerational dietary transitions on historic and future human exposure to persistent organic pollutants in the Arctic

► We present a method for quantifying effects of dietary transitions on POPs exposure. ► Reduced emissions (1980 to 2020) decreases PCB-153 body burden by 6-13 fold. ► Dietary transitions account for an additional factor of 2-50 fold decrease. ► Dietary transitions contribute to the variability within and between populations. ► Dietary transition details are required to interpret human biomonitoring data in the Arctic.