Using a photochemical model to assess the horizontal, vertical and time distribution of PM2.5 in a complex area: Relationships between the regional and local sources and the meteorological conditions

► A first attempt of PM2.5 description in Venice with photochemical model was studied. ► A no-boundary simulation was performed to assess local and regional contributions. ► Good results was reached and discussed in relation to the complex meteorology. ► PM10 was well predicted for all seasons and in all the sampled sites. ► Model tendency to overestimate PM2.5 was discussed and related to PM2.5/PM10 ratio.