Exploring an ecotoxicity database with the OECD (Q)SAR Toolbox and DRAGON descriptors in order to prioritise testing on algae, daphnids, and fish

► We compared acute toxicity data for algae, daphnids, and fish. ► Chemicals were described with categorizations and quantitative descriptors. ► Cross-species' differences in sensitivity are shown for particular chemical classes. ► Structure-activity relationships were mainly related to hydrophobicity. ► Interspecies correlations were high.