Chemical and isotopic seismic precursory signatures in deep groundwater: Cause and effect

► The first of its kind exploratory research in the Stable Continental Regions. ► The research methodology showed the aquifer response to tectonic stresses. ► Cyclic hydrochemical changes helped in foreseeing the earthquake. ► Real time EC measurement and on-line data transfer may help in short term forecasting. ► The research highlights the recurrence of M > 5 earthquakes every 5 year.