کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6344306 1620722 2016 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
In vitro study on the aerosol emitted from the DPI inhaler under two unsteady inhalation profiles
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات علم هواشناسی
پیش نمایش صفحه اول مقاله
In vitro study on the aerosol emitted from the DPI inhaler under two unsteady inhalation profiles
چکیده انگلیسی
Results presented in the paper confirm its assumption to be true. Different inhalation curves were associated with substantially different inhaler performances. The quicker and more forceful curve II produced better dispersion. Aerosol dynamics is particularly susceptible to the strong aerodynamic effects of unsteadiness acquired from relatively small values of flow rates. The initial part of inspiration may contribute to achieving higher respirable dose content before the peak inspiratory flow is attained. Deaggregation upon impactions with chamber wall and subsequent collisions with grid are assumed to produce desired fine particle fraction. The paper elucidates the relevance of considering time-varying character of inspiration.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Aerosol Science - Volume 101, November 2016, Pages 104-117
نویسندگان
, , ,