کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6400727 1330877 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Liposoluble vitamin encapsulation in shell-core microparticles produced by ultrasonic atomization and microwave stabilization
ترجمه فارسی عنوان
کپسوله کردن ویتامین چسبیده در میکروپارس های پوسته هسته تولید شده توسط اتمسفر اولتراسونیک و تثبیت مایکروویو
کلمات کلیدی
میکرو ذرات هسته شل، ویتامین ها، تحویل مواد مخدر، انرژی التراسونیک، خشک کردن مایکروویو،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی


- An ultrasonic atomization/microwave drying combined technique was improved.
- Shell-core alginate/pluronic microparticles were able to encapsulate vitamin D2.
- The particles had enteric behavior: interesting feature for oral administration.
- D2 degradation in microparticles was avoided for several months of storage.

Encapsulation may protect unstable, fat soluble vitamins such as vitamin D2 (ergocalciferol). However, encapsulation by the solvent extraction and/or evaporation techniques can require toxic organic solvents, which greatly increase processing costs. The objective of this study was to evaluate the effect on ergocalciferol encapsulation by a combination of the ionic gelation method with the ultrasonic atomization and microwave drying. Optimization of manufacturing parameters included the addition of pluronic-F127 to the core solution at 1.5% w/w to increase the encapsulation efficiency to nearly 92%, greatly improving performance compared to Tween 80 at 0.5% w/w. Microwave treatment at 230 W promoted the recovery of 100% of the ergocalciferol and reduced drying times to about 30 min, while 690 W degraded 40% of the D2. In contrast, the conventional heating degraded 17% of the ergocalciferol during 12 h of processing. By all the applied methods, microparticles were produced with similar gastoresistance properties of less than 10% release at pH of 1.0, to nearly 100% release at pH of 6.8 and 240 min of dissolution. Analysis showed limited ergocalciferol degradation after 5 months of storage.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: LWT - Food Science and Technology - Volume 64, Issue 1, November 2015, Pages 149-156
نویسندگان
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