Polyphenol input to the antioxidant activity of yerba mate (Ilex paraguariensis) extracts

► Processing modified the extracts antioxidant capacity and polyphenol composition. ► Based on activity and polyphenol level, pre-dried leaves were the best raw material. ► Extracts reduced rancidity in oil and emulsions. Higher doses were less active in oil. ► The model predicted the activity of a blend of 5 polyphenols present in the extract. ► The model detected the 4 best and 3 worst performing polyphenol combinations.