کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6452896 1418396 2017 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Production of Hydrophobins from fungi
ترجمه فارسی عنوان
تولید هیدروفوبین از قارچ ها
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی


- Focuses on different sources of hydrophobins and diverse attempts made for production.
- Gives overview of different traditional production methods used such as use of wild type fungi, solid state fermentation etc.
- Recombinant production methods for Hydrophobins are discussed in details.

Hydrophobins (HPs) are industrially important surface active, amphipathic proteins produced by fungi. There are many applications reported for HPs in the literature notably as, agents for enhancing bioavailability of water insoluble drugs, food stabilizers, antifouling agents for biomedical devices like catheters, fusion partner for recombinant proteins for purification, low friction coatings on biomaterials, immobilizing enzymes in biosensors, etc. However, there are limitations for industrial scale production of HPs. Various methods have been reported for their production e.g. use of wild fungi from natural hydrophobic environments, use of modified bioreactors for submerged and solid state fermentation and recombinant homologous as well as heterologous microbes. Knowing the industrial importance of HPs many reviews have been published focusing on technical and medical applications of these proteins; however there is no comprehensive overview of HP production in the literature. This review summarizes the efforts made to improve yields of HPs by various bioprocesses and also highlights the strategies designed to overcome problems of low yield of HPs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Process Biochemistry - Volume 61, October 2017, Pages 1-11
نویسندگان
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