کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6462048 | 1421979 | 2017 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Identification of MDMB-FUBINACA in commercially available e-liquid formulations sold for use in electronic cigarettes Identification of MDMB-FUBINACA in commercially available e-liquid formulations sold for use in electronic cigarettes](/preview/png/6462048.png)
- Three commercially available e-liquids were analyzed by DART-MS, GC-MS, SPME-GC-MS and HS-GC-FID for their contents.
- MDMB-FUBINACA, a cannabimimetic drug, was found to be the major active ingredient.
- MDMB-FUBINACA was successfully aerosolized by an electronic cigarette.
- Ethanol and numerous flavorants were also detected in the e-liquids.
MDMB-FUBINACA (aka MDMB(N)-Bz-F), chemical name Methyl (S)-2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate, a designer drug or a new psychoactive substance (NPS), was identified in three commercially available e-liquids formulated for electronic cigarette use. The e-liquids were evaluated using direct analysis in real time ion source attached to a time of flight mass spectrometer (DART-MS) and gas chromatograph mass spectrometer (GC-MS) to identify active ingredients/drugs, flavorants, and other possible constituents. The e-liquids were also evaluated for alcohol content by headspace gas chromatography with flame ionization detector (HS-GC-FID). The aerosol produced from the e-liquids by use of an e-cigarette was analyzed by solid phase micro-extraction gas chromatography mass spectrometry (SPME-GC-MS) to ensure delivery of the active ingredient/drug. Propylene glycol, vegetable glycerin, MDMB-FUBINACA, alcohol content and a flavor profile were determined for each of the e-liquids. MDMB-FUBINACA was determined to be the major active ingredient in all three e-liquids and was successfully detected by SPME-GC-MS in the aerosol generated by a KangerTech Aerotank clearomizer/electronic cigarette.
195
Journal: Forensic Science International - Volume 271, February 2017, Pages 92-97