کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6477020 1426210 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Solubility measurement and modelling of ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)-2-thiophenecarboxylate in four groups mixed solvents
ترجمه فارسی عنوان
اندازه گیری و تجزیه و تحلیل حلالیت اتیل 5-آمین-4-سیانو -3- (2-اتسوک-2-اکئوکتیل) -2-تیوفن کربوکسیلات در چهار گروه حلال های مخلوط
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی


• Solubility of ACET in four groups mixed solvents were determined.
• Solubility data were correlated and calculated by three cosolvency models.
• The standard dissolution enthalpy for the dissolution processes were calculated.

The solubility of ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)-2-thiophenecarboxylate (ACET) in binary (acetone + methanol), (acetone + ethanol), (acetone + 1-butanol) and (acetone + isopropanol) solvent mixtures was investigated by the isothermal dissolution equilibrium method under 101.3 kPa. This study was carried out at different mass fractions of acetone ranging from 0.1 to 0.9 at T = (273.15–318.15) K. For the nine groups with each solvent mixture studied, the solubility of ACET in the mixed solutions increased with increasing temperature and mass fraction acetone. At the same temperature and mass fraction of acetone, the solubility of ACET was greater in (acetone + methanol) than in the other three solvent mixtures. The experimental solubility values were correlated by three co-solvency models (Jouyban-Acree model, van’t Hoff-Jouyban-Acree model and Apelblat- Jouyban-Acree model). The relative average deviations (RAD) and the root-mean-square deviations (RMSD) were all less than 1.49 × 10−2 and 8.99 × 10−4, respectively. The Apelblat-Jouyban-Acree model provided best representation of the experimental solubility. Furthermore, the standard molar enthalpy of the ACET during the dissolving process (ΔsolHoΔsolHo) was also derived in this work, and the results showed that the dissolution process is endothermic. The experimental solubility and the models used in this work would be helpful in purifying of ACET from its crude mixtures.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Chemical Thermodynamics - Volume 103, December 2016, Pages 414–422