کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6481695 | 1540227 | 2016 | 12 صفحه PDF | دانلود رایگان |
- Silver nanoparticles were synthesized using sodium alginate.
- Sodium alginate act as reducing and stabilizing agent.
- Na-Alg-s-AgNPs@SiO2 nanohybrid prepared by sol-gel method.
- Nanohybrid exhibited promising broad-spectrum antimicrobial activity.
- Nanohybrid may be used effectively in long-term antimicrobial applications.
Due to the problem of resistance of many infectious agents to the usual treatments, this study addresses the ways of obtaining and using new sodium alginate stabilized-silver/mesoporous silica (Na-Alg-s-AgNPs@SiO2) nanohybrid as antimicrobial agents. Capping AgNPs with a shell of mesoporous SiO2 is a system to build the increase biocompatibility of AgNPs. In this work, we report a simple and green way to deal with setting up a uniform sodium alginate-stabilized silver nanoparticles embedded mesoporous silica (Na-Alg-s-AgNPs@SiO2 nanohybrid). The synthesized nanocomposite was characterized using transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectra, and ultraviolet-visible (UV-vis) absorption spectra, which exhibited that AgNPs with average of size of â¼7Â nm were consistently and compactly deposited in the nanocomposite. The nanohybrid demonstrated excellent antibacterial activity against both Gram negative (âve) and Gram positive (+ve) bacteria. Thus, the developed Na-Alg-s-AgNPs@SiO2 nanohybrid has a potential to be used for various antibacterial applications in biotechnology and biomedical fields.
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Journal: International Journal of Biological Macromolecules - Volume 93, Part A, December 2016, Pages 712-723